Juniper Publishers: The Role of Antioxidant Supplementation in Endometriosis Therapy
JUNIPER PUBLISHERS- JOURNAL OF GYNECOLOGY AND WOMEN’S HEALTH Journal of Gynecology and Women’s Health-Juniper Publishers Authored by Annika Sinha* Abstract Endometriosis is a benign, estrogen-dependent disorder, characterized by the presence of ectopic lesions in extra-uterine regions of body, including the ovaries, peritoneum, and even the thoracic cavity. Though the pathophysiology of endometriosis is relatively unknown, disease itself is characterized by cell survival, oxidative stress, cellular proliferation, excessive adhesion, inflammation, and angiogenesis [Matsuzaki]. Though endometriomas are not malignant, this atypical tissue can spread throughout the female reproductive tract, causing chronic pain, infertility, and abnormal bleeding. Approximately 1 in 10 women suffe...