Juniper Publishers | Journal of Gynecology and Women’s Health

Value of Urocortin as a Marker for Preterm Labor-Journal of Gynecology and Women’s Health-Juniper Publishers


JUNIPER PUBLISHERS- JOURNAL OF GYNECOLOGY AND WOMEN’S HEALTH




VALUE OF UROCORTIN AS A MARKER FOR PRETERM LABOR

Authored by Haitham Abdel Mohsen Sabaa

Introduction: Preterm delivery is responsible for considerable neonatal morbidity and mortality, accurate predication could decrease such complications different biological markers have been suggested to predict preterm labor, maternal plasma urocortin level was suggested as a marker.
Methods: 100 women diagnosed with threatened preterm labor were included in the study and their blood level of urocortin was measured at admission time and its level was correlated with the occurrence of established preterm labor.
Results: The best cutoff criterion of plasma urocortin level was more than 365.2 pg/ml with sensitivity at 87% (CI: 73.7 – 95.1) and specificity of 100% (CI: 93.4 – 100). Followingly the positive predictive value for this cutoff point (>365.2 pg/ml) was 100% (CI: 91.2 – 100) & the negative predictive value was 90% (CI: 79.5 – 96.2).
Conclusion: Our study showed that maternal plasma urocortin can be used for prediction of preterm delivery as an independent factor.

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