The Effect of Eccentric Exercise with Variations in Rest Interval on Creatine Kinase and Lactate Dehydrogenase Enzymes in Sedentary Young Men

 Abstract

Various studies have demonstrated that different rest Intervals and set -repetition has a significant effect on hormonal and metabolic responses. This factors can lead to different muscle damage responses. 20 untrained subjects (25.4±0.068 years, height 1.74±0.97cm and weight 30.8±8.48kg) in three sessions of eccentric resistance exercise with 24 hours rest between each session Participated in this study. Subjects were divided into 2 groups of 10 subjects who performed 50 eccentric contractions with different number of 5 sets, 5 repetitions, and the interset rest interval 1 and 3 minutes with 85% of one repetition maximum (1RM). Creatine Kinase and Lactate Dehydrogenase were measured immediately before , immediately after each session and 24 hours after the last training session. Variance analysis with repeated measurment and Bonferroni post-hoc test were used for statistical analysis of data. There is no significant difference in Creatine Kinase and Lactate Dehydrogenase between four groups at different time points. (P <0.05). The repetition of eccentric exercise for three consecutive days causes muscle damage that is independent of manipulating the interset rest intervals. 

 

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